Kitasato Shibasaburō
Japanese bacteriologist who co-discovered the plague bacillus.
Kitasato Shibasaburō was a Japanese bacteriologist. He is the co-discoverer of the bacillus responsible for the bubonic plague (1894, with Alexandre Yersin). The source does not provide his birth or death dates, nor does it mention a barony, a Nobel nomination, or work with Emil von Behring on diphtheria antitoxin serum and tetanus therapy.
- nationality
- Japanese
- known_for
- Co-discovery of bubonic plague bacillus
Lore & Background
The source states that the Japanese government sent Kitasato Shibasaburō to investigate the plague in Hong Kong. On 5 June, Kitasato departed Yokohama on SS City of Rio de Janeiro with a team of 5, arriving in Hong Kong on 12 June. On 14 June, Kitasato discovered that the bacillus, now known as Yersinia pestis, was the direct cause of the plague. However, he was doubtful of its significance as the autopsy was done 11 hours after death. His finding was reported by James Alfred Lowson to The Lancet, and his report was published a week later, on 25 August. The source notes that Kitasato's description lacked precision, and the report was riddled with doubts and confusion. Kitasato insisted that his organism was Gram-positive, while Yersin correctly described his as Gram-negative. Kitasato described his blood organism as diplococcal and his bubo organism as bacillary, causing confusion and suggesting to some that his cultures were contaminated by the pneumococcus. In the ensuing months and years, Kitasato asserted that his bacillus was different from that of Yersin. The source does not provide details on Kitasato's early life, education, or other career achievements.
Reader's Guide
Kitasato Shibasaburō's significance lies in his co-discovery of the bubonic plague bacillus in Hong Kong in 1894. He arrived on 12 June and discovered the bacillus on 14 June, three days before Yersin's arrival. However, his findings were marked by confusion: he described his organism as Gram-positive, while Yersin correctly identified it as Gram-negative. Kitasato also described his blood organism as diplococcal and his bubo organism as bacillary, leading to suggestions of contamination by pneumococcus. Despite these issues, Kitasato's report was published in The Lancet on 25 August 1894. The source does not cover his work on tetanus, diphtheria, or his later career in Japan.
Did You Know?
- Kitasato Shibasaburō departed Yokohama on 5 June 1894 on the SS City of Rio de Janeiro with a team of 5 to investigate the plague in Hong Kong.
- He discovered the plague bacillus on 14 June 1894, three days before Alexandre Yersin arrived in Hong Kong.
- Kitasato's initial report was published in The Lancet on 25 August 1894, just a week after his finding.
- Kitasato insisted his organism was Gram-positive, while Yersin correctly described his as Gram-negative.
- Kitasato described his blood organism as diplococcal and his bubo organism as bacillary, causing confusion and suggesting possible contamination by pneumococcus.
Frequently Asked Questions
Who is Kitasato Shibasaburō?
Kitasato Shibasaburō (1853–1931) was a Japanese physician and bacteriologist born in Okuni village, Higo Province. He is best remembered for his groundbreaking work in identifying infectious disease agents and advancing serotherapy in the late 19th century.
What is Kitasato Shibasaburō most famous for?
He is celebrated as the co-discoverer of the bubonic plague bacillus during the 1894 Hong Kong outbreak, a finding made almost simultaneously with Alexandre Yersin. His collaborative work with Emil von Behring on diphtheria antitoxin serum and tetanus therapy also laid the groundwork for modern serotherapy.
How did Kitasato Shibasaburō discover the plague bacillus?
During the 1894 epidemic in Hong Kong, Kitasato isolated the infectious agent responsible for bubonic plague. His identification of the bacterium was made nearly at the same time as Yersin's, which is why both are credited as co-discoverers.
Did Kitasato Shibasaburō win a Nobel Prize?
He did not win, but he was nominated for the very first Nobel Prize in Physiology or Medicine in 1901. The prize ultimately went to others that year, though his contributions to serotherapy and plague research were widely recognized by the scientific community.
What lasting legacy did Kitasato Shibasaburō leave in medicine?
Beyond his plague and antitoxin research, he founded the Kitasato Institute, which became a major center for medical and biological research in Japan. His work on tetanus and diphtheria therapies helped establish the principles of using antitoxin serums to treat infectious diseases.
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